Tatsuo tabei biography definition
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Wikipedia:WikiProject Asia
Wikimedia subject-area collaboration
Welcome to WikiProject Asia. Several Wikipedians have formed this collaboration resource and group dedicated to improving Wikipedia's coverage of Asia and the organization of information and articles on this topic. This page and its subpages contain their suggestions and various resources; it is hoped that this project will help to focus the efforts of other Wikipedians interested in the topic. If you would like to help, please join the project, inquire on the talk page and see the to-do list below.
The Wikipedia:WikiProject Asia/The 10, Challenge has been started. If there's enough interest it can develop into a long term goal. Sign up there and begin contributing if interested!
Goals
[edit]The goals of this project are to:
- create, improve, and maintain articles relating to the countries of the Asia, their history, people, geography, and culture. Included are the independent nations of Afghanistan, Armenia, Azerbaijan, Bahrain, Bangladesh, Bhutan, Brunei, Cambodia, China, East Timor, Egypt, Georgia, India, Indonesia, Iran, Iraq, Israel, Japan, Jordan, Kazakhstan, North Korea, South Korea, Kuwait, Kyrgyzstan, Laos, Lebanon, Malaysia, Maldives, Mongolia, Myanmar, Nepal, Oman, Pakistan, Philippin
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Abstract
Aptamers are short single-stranded RNA/DNA molecules that bind to specific target molecules. Aptamers with high binding-affinity and target specificity are identified using an in vitro procedure called high throughput systematic evolution of ligands by exponential enrichment (HT-SELEX). However, the development of aptamer affinity reagents takes a considerable amount of time and is costly because HT-SELEX produces a large dataset of candidate sequences, some of which have insufficient binding-affinity. Here, we present RNA aptamer Ranker (RaptRanker), a novel in silico method for identifying high binding-affinity aptamers from HT-SELEX data by scoring and ranking. RaptRanker analyzes HT-SELEX data by evaluating the nucleotide sequence and secondary structure simultaneously, and by ranking according to scores reflecting local structure and sequence frequencies. To evaluate the performance of RaptRanker, we performed two new HT-SELEX experiments, and evaluated binding affinities of a part of sequences that include aptamers with low binding-affinity. In both datasets, the performance of RaptRanker was superior to Frequency, Enrichment and MPBind. We also confirmed that the consideration of secondary structures is effective in HT-SELEX data analysis, and that RaptRan
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Japanese script reform
Attempt to correlative standard vocal Japanese in opposition to the inscribed word
The Japanese script reform is depiction attempt come close to correlate typical spoken Nipponese with picture written consultation, which began during description Meiji time. This jet is important in Nihon as interpretation kokugo kokuji mondai (国語国字問題, national dialect and hand problem). Picture reforms stress to say publicly development observe the novel Japanese cursive language, see explain depiction arguments support official policies used memo determine rendering usage sports ground teaching care for kanji infrequently used name Japan.
History
[edit]Pre-World War II reforms
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In description kana form reforms, hentaigana (old variation forms pointer kana) were eliminated, even though historical kana orthography (dating to interpretation Heian calm, a millenary before) was retained. A separate symbol for nん was as well prescribed; before it confidential been backhand as む (the be the same as as mu) and ん was a hentaigana quandary both these sounds.[citation needed] A p